Buijs, R.M. and Kreier, F. (2006) The metabolic syndrome: a brain disease? Journal of neuroendocrinology, 18(9), 715-716. ISSN 09538194. doi: 10.1111/j.1365-2826.2006.01456.x.
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The incidence of obesity with, as consequence, a rise in associated diseases such as diabetes, hypertension and dyslipidemia--the metabolic syndrome--is reaching epidemic proportions in industrialized countries. Here, we provide a hypothesis that the biological clock which normally prepares us each morning for the coming activity period is altered due to a modern life style of low activity during the day and late-night food intake. Furthermore, we review the anatomical evidence supporting the proposal that an unbalanced autonomic nervous system output may lead to the simultaneous occurrence of diabetes type 2, dyslipidemia, hypertension and visceral obesity.
|Additional Information:||doi: 10.1111/j.1365-2826.2006.01456.x|
|Institutes:||Netherlands Institute for Neuroscience (NIN)|
|Deposited On:||13 Feb 2009 17:14|
|Last Modified:||10 Dec 2009 13:14|
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