Luijpen, M.W. and Swaab, D.F. and Sergeant, J.A. and Dijk, K.R.A. and Scherder, E.J. (2005) Effects of transcutaneous electrical nerve stimulation (TENS) on memory in elderly with mild cognitive impairment. Behavioural brain research, 158(2), 349-357. ISSN 01664328. doi: 10.1016/j.bbr.2004.09.017.
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In previous studies, transcutaneous electrical nerve stimulation (TENS) was shown to have a positive effect on memory in Alzheimer's disease (AD) patients. Moreover, the reported effects appeared to be more beneficial in early stages of Alzheimer's disease compared to later stage intervention. Based on this stage-dependency, the present study examined the effects of TENS on memory in a preclinical stage of AD, i.e. in subjects with mild cognitive impairment (MCI). Our results suggest that TENS did not improve memory in a MCI population. Mechanisms that might underlie the absence of positive effects of the TENS treatment in a MCI population are discussed.
|Additional Information:||doi: 10.1016/j.bbr.2004.09.017|
|Institutes:||Netherlands Institute for Neuroscience (NIN)|
|Deposited On:||13 Feb 2009 17:14|
|Last Modified:||10 Dec 2009 13:14|
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