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APCmin tumors need a SPARC

Gregorrieff, A. and Clevers, J.C. (2007) APCmin tumors need a SPARC. Gut, 56. doi:10.1136/gut.2007.122135; Publication ehaed of print..

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The interaction between cancer cells and their microenviroment strongly influences growth and invasiveness of neoplasia. In this issue of Gut, a new study identifies the extracellular matrix (ECM) component, SPARC, as a critical determinant of tumor burden in the APCmin/+ model of intestinal cancer.

Item Type:Article
Additional Information:doi:10.1136/gut.2007.122135; Publication ehaed of print.
Institutes:Hubrecht Instituut
ID Code:3770
Deposited On:13 Feb 2009 17:14
Last Modified:10 Dec 2009 13:14

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