De Laender, F. and Van Oevelen, D.J. and Middelburg, J.J. and Soetaert, K.E.R. (2010) Uncertainties in ecological, chemical and physiological parameters of a bioaccumulation model: implications for internal concentrations and tissue based risk quotients. Ecotoxicology and Environmental Safety, 73, 240-246. ISSN 0147-6513.
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Official URL: http://dx.doi.org/10.1016/j.ecoenv.2009.11.011
Abstract
Bioaccumulationmodelspredictinternalcontaminantconcentrations(ci) usingecological,chemical and physiologicalparameters.Hereweanalysetheeffectofuncertaintiesontheseparameterson bioaccumulationmodelpredictions.Simultaneouslyconsideringtheuncertaintiesonallthese parametersinabioaccumulationmodelresultedinuncertaintyrangesof ci that increasedwiththe octanolwaterpartitioncoefficient Kow and reachedmaximaofupto1.25logunitsformesozooplankton and upto1.45logunitsfishatlog Kow=8.Aglobalsensitivityanalysis(SA)wasperformedtorankthe contributionofdifferentparameterstotheobserveduncertainty.TheSAdemonstratedthatthis interspeciesdifferenceresultedpredominantlyfromuncertainproductionratesoffish.The Kow, the water concentrationandorganiccarbon–octanolproportionalityconstantwereimportantdriversof uncertaintyon ci for bothspecies.Atissuebasedriskquotient(RQtissue) combininguncertaintyon ci with realistictissuebasedeffectthresholdsindicatedthatfishwereupto10timesmoreprobableto have RQtissue41 thanmesozooplankton,dependingontheconsideredthresholdvalue.Conventional exposurebasedriskquotientswereupto5timeslessprobabletoexceedonethanwerecorresponding RQtissue, andthisforbothspecies
| Item Type: | Article |
|---|---|
| Institutes: | Nederlands Instituut voor Ecologie (NIOO) |
| ID Code: | 6496 |
| Deposited On: | 01 Jul 2010 02:00 |
| Last Modified: | 24 Apr 2012 16:43 |
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