Kaaij, L. J. and Ketting, R.F. (2010) Dcr1 tracked down. Developmental Cell, 18, 6-7. ISSN 1534-5807.
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Official URL: http://dx.doi.org/10.1158/0008-5472.CAN-10-0315
RNAi is essential for pericentromeric heterochromatic formation in S. pombe, and although Dcr1, the initiator protein of this process, has been biochemically well described, its subcellular localization has remained elusive. In this issue of Developmental Cell, Emmerth et al. now show that Dcr1 is dynamically shuttling between nucleus and cytoplasm, adding new insight into the subcellular mechanics of RNAi.
|Deposited On:||04 Jan 2011 01:00|
|Last Modified:||07 Sep 2011 17:01|
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