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Rat traps: filling the toolbox for manipulating the rat genome

Boxtel van, R. and Cuppen, E. (2010) Rat traps: filling the toolbox for manipulating the rat genome. Genome Biology, 11, 217-. ISSN 1474-760X.

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Official URL: http://dx.doi.org/10.1186/gb-2010-11-9-217

Abstract

The laboratory rat is rapidly gaining momentum as a mammalian genetic model organism. Although traditional forward genetic approaches are well established, recent technological developments have enabled efficient gene targeting and mutant generation. Here we outline the current status, possibilities and application of these techniques in the rat.

Item Type:Article
Institutes:Hubrecht Instituut
ID Code:9527
Deposited On:11 Feb 2011 01:00
Last Modified:07 Sep 2011 17:01

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