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Items where Institute is "Hubrecht Instituut" and Year is 2010

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Number of items: 95.

Article

Akker van den, W. M. and Durston, A.J. and Spaink, H.P. (2010) Identification of hoxb1b downstream genes: hoxb1b as a regulatory factor controlling transcriptional networks and cell movement during zebrafish gastrulation. International journal of developmental biology, 54, 55-62. ISSN 0214-6282.

Arensbergen van, J. and Garcia-Hurtado, J. and Moran, I. and Maestro, M. A. and Xu, X. and Casteele Van de, M. and Skoudy, A. L. and Palassini, M. and Heimberg, H. and Ferrer, J. (2010) Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program. Genome Research, 20, 722-32. ISSN 1088-9051.

Ashton, G. H. and Morton, J. P. and Myant, K. and Phesse, T. J. and Ridgway, R.A. and Marsh, V. and Wilkins, J. A. and Athineos, D. and Muncan, V. and Kemp, R. and Neufeld, K. and Clevers, H. and Brunton, V. and Winton, D. J. and Wang, X. and Sears, R. and Clarke, A.R. and Frame, M. C. and Sansom, O.J. (2010) Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling. Developmental Cell, 19, 259-69. ISSN 1534-5807.

Atanur, S. S. and Birol, I. and Guryev, V. and Hirst, M. and Hummel, O. and Morrissey, C. and Behmoaras, J. and Fernandez-Suarez, X.M. and Johnson, M. D. and McLaren, W. M. and Patone, G. and Petretto, E. and Plessy, C. and Rockland, K. S. and Rockland, C. and Saar, K. and Zhao, Y. and Carninci, P. and Flicek, P. and Kurtz, T. and Cuppen, E. and Pravenec, M. and Hubner, N. and Jones, S. and Birney, E. and Aitman, T. (2010) The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance. Genome Research, 20, 791-803. ISSN 1088-9051.

Barker, N. and Bartfeld, S. and Clevers, H. (2010) Tissue-resident adult stem cell populations of rapidly self-renewing organs. Cell Stem Cell, 7, 656-70. ISSN 1934-5909.

Barker, N. and Clevers, H. (2010) Leucine-rich repeat-containing G-protein-coupled receptors as markers of adult stem cells. Gastroenterology, 138, 1681-96. ISSN 0016-5085.

Barker, N. and Clevers, H. (2010) Lineage tracing in the intestinal epithelium. Current Protocols in Stem Cell Biology, Chapter 5, Unit5A-4. ISSN 1941-7322.

Barker, N. and Huch, M. and Kujala, P. and Wetering van de, M.L. and Snippert, H.J.G. and Es van, J.H. and Sato, T. and Stange, D.E. and Begthel, H.L. and Born van den, M.M.W. and Danenberg, E.M. and Brink van den, S. and Korving, J. and Abo, A. and Peters, P. and Wright, N. and Poulsom, R. and Clevers, H. (2010) Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell, 6, 25-36. ISSN 1934-5909.

Beqqali, A. and Monshouwer-Kloots, J. and Monteiro, R. and Welling, M. and Bakkers, J. and Ehler, E. and Verkleij, A.J. and Mummery, C.L. and Passier, R. (2010) CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function. Journal of Cell Science, 123, 1141-50. ISSN 0021-9533.

Berezikov, E. and Liu, N. and Flynt, A. S. and Hodges, E. and Rooks, M. and Hannon, G.J. and Lai, E.C (2010) Evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Nature Genetics, 42, 6-9; author reply 9-10. ISSN 1061-4036.

Berezikov, E. and Robine, N. and Samsonova, A. and Westholm, J. O. and Naqvi, A. and Hung, J. H. and Okamura, K. and Dai, Q. and Bortolamiol-Becet, D. and Martin, R. and Zhao, Y. and Zamore, P. D. and Hannon, G.J. and Marra, M. A. and Weng, Z. and Perrimon, N. and Lai, E.C (2010) Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. Genome Research. ISSN 1088-9051.

Bialecka, M. and Wilson, V. and Deschamps, J. (2010) Cdx mutant axial progenitor cells are rescued by grafting to a wild type environment. Developmental Biology, 347, 228-34. ISSN 0012-1606.

Boer de, H. and Hovens, M. and Oeveren van, A. and Snoep, J. and Koning de, E. and Tamsma, J. and Huisman, M. and Rabelink, T. J. and Zonneveld van, A.J. (2010) Human CD34+/KDR+ Cells Are Generated From Circulating CD34+ Cells After Immobilization on Activated Platelets. Arteriosclerosis, Thrombosis and Vascular Biology. ISSN 1079-5642.

Bongers, G. and Maussang, D. and Muniz, L. R. and Noriega, V. M. and Fraile-Ramos, A. and Barker, N. and Marchesi, F. and Thirunarayanan, N. and Vischer, H. F. and Qin, L. and Mayer, L. and Harpaz, N. and Leurs, R. and Furtado, G. C. and Clevers, H. and Tortorella, D. and Smit, M. J. and Lira, S. A. (2010) The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice. Journal of Clinical Investigation, 120, 3969-78. ISSN 0021-9738.

Boxtel van, R. and Cuppen, E. (2010) Rat traps: filling the toolbox for manipulating the rat genome. Genome Biology, 11, 217-. ISSN 1474-760X.

Boxtel van, R. and Gould, M. and Cuppen, E. and Smits, B.M. (2010) ENU mutagenesis to generate genetically modified rat models. Methods in Molecular Biology, 597, 151-67. ISSN 1064-3745.

Boxtel van, R. and Vroling, B. and Toonen, P.W. and Nijman, I.J. and Roekel van, H. and Verheul, M. and Baakman, C. and Guryev, V. and Vriend, G. and Cuppen, E. (2010) Systematic generation of in vivo G protein-coupled receptor mutants in the rat. Pharmacogenomics J. ISSN 1470-269X.

Bredenoord, A. L. and Kroes, H.Y. and Cuppen, E. and Parker, M. and Delden van, J.J.M. (2010) Disclosure of individual genetic data to research participants: the debate reconsidered. Trends in Genetics, 27, 41-7. ISSN 0168-9525.

Buecker, C. and Geijsen, N. (2010) Different flavors of pluripotency, molecular mechanisms, and practical implications. Cell Stem Cell, 7, 559-64. ISSN 1934-5909.

Bussmann, J. and Bos, F. L. and Urasaki, A. and Kawakami, K. and Duckers, H.J. and Schulte-Merker, S. (2010) Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk. Development, 137, 2653-7. ISSN 0950-1991.

Clevers, H. (2010) Eigen stamcellen eerst. De Volkskrant. ISSN ....-.....

Clevers, H. (2010) Transplantatie van gekweekte darmpjes moet baby redden. Trouw. ISSN ....-.....

Clevers, H. (2010) The next step in tissue culture. Utrecht Medical Sciences.

Cole, A. M. and Myant, K. and Reed, K. R. and Ridgway, R.A. and Athineos, D. and Brink Van den, G. R. and Muncan, V. and Clevers, H. and Clarke, A.R. and Sicinski, P. and Sansom, O.J. (2010) Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss. Cancer Research, 70, 8149-58. ISSN 0008-5472.

Cole, A. M. and Ridgway, R.A. and Derkits, S. E. and Parry, L. and Barker, N. and Clevers, H. and Clarke, A.R. and Sansom, O.J. (2010) p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium. EMBO Molecular Medicine, 2, 472-86. ISSN 1757-4676.

Correa, R. L. and Steiner, F.A. and Berezikov, E. and Ketting, R.F. (2010) MicroRNA-directed siRNA biogenesis in Caenorhabditis elegans. PLoS Genetics, 6, e1000903-. ISSN 1553-7390.

Cuppen, E. (2010) Alle kanten op met de genenkaart; Moet je de patiƫnt alles vertellen? De Volkskrant. ISSN ....-.....

Cuppen, E. (2010) DNA isolation from rat tail or ear. Cold Spring Harbor Protocols, 2010, pdb-prot5434. ISSN 1559-6095.

Demarque, M. D. and Nacerddine, K. and Neyret-Kahn, H. and Andrieux, A. and Danenberg, E.M. and Jouvion, G. and Bomme, P. and Hamard, G. and Romagnolo, B. and Terris, B. and Cumano, A. and Barker, N. and Clevers, H. and Dejean, A. (2010) Sumoylation by Ubc9 Regulates the Stem Cell Compartment and Structure and Function of the Intestinal Epithelium in Mice. Gastroenterology. ISSN 0016-5085.

Duc le, Q. and Shi, Q. and Blonk, I. and Sonnenberg, A. and Wang, N. and Leckband, D. and Rooij de, J. (2010) Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner. Journal of Cell Biology, 189, 1107-15. ISSN 0021-9525.

Es van, J.H. and Geest de, N. and Born van den, M.M.W. and Clevers, H. and Hassan, B. A. (2010) Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors. Nature Communications, 1, 1-5. ISSN 2041-1723.

Evangelou, E. and Valdes, A. M. and Kerkhof, H. J. and Styrkarsdottir, U. and Zhu, Y. and Meulenbelt, I. and Lories, R. J. and Karassa, F. B. and Tylzanowski, P. and Bos, S. D. and Akune, T. and Arden, N. K. and Carr, A. and Chapman, K. and Cupples, L. A. and Dai, J. and Deloukas, P. and Doherty, M. and Doherty, S. and Engstrom, G. and Gonzalez, A. and Halldorsson, B. V. and Hammond, C.J. and Hart, D. J. and Helgadottir, H. and Hofman, A. and Ikegawa, S. and Ingvarsson, T. and Jiang, Q. and Jonsson, H. and Kaprio, J. and Kawaguchi, H. and Kisand, K. and Kloppenburg, M. and Kujala, U. M. and Lohmander, L. S. and Loughlin, J. and Luyten, F. P. and Mabuchi, A. and McCaskie, A. and Nakajima, M. and Nilsson, P. M. and Nishida, N. and Ollier, W. E. and Panoutsopoulou, K. and Putte van de, T. and Ralston, S. H. and Rivadeneira, F. and Saarela, J. and Schulte-Merker, S. and Shi, D. and Slagboom, P. E. and Sudo, A. and Tamm, A. and Thorleifsson, G. and Thorsteinsdottir, U. and Tsezou, A. and Wallis, G. A. and Wilkinson, J. M. and Yoshimura, N. and Zeggini, E. and Zhai, G. and Zhang, F. and Jonsdottir, I. and Uitterlinden, A.G. and Felson, D. T. and Meurs van, J. B. and Stefansson, K. and Ioannidis, J. P. and Spector, T.D. (2010) Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Annals of the Rheumatic Diseases. ISSN 0003-4967.

Geudens, I. and Herpers, R. and Hermans, K. and Segura, I. and Almodovar Ruiz de, C. and Bussmann, J. and Smet De, F. and Vandevelde, W. and Hogan, B.M. and Siekmann, A. and Claes, F. and Moore, J. and Pistocchi, A. S. and Loges, S. and Mazzone, M. and Mariggi, G. and Bruyere, F. and Cotelli, F. and Kerjaschki, D. and Noel, A. and Foidart, J. M. and Gerhardt, H. and Ny, A. and Langenberg, T. and Lawson, N. and Duckers, H.J. and Schulte-Merker, S. and Carmeliet, P. and Dewerchin, M. (2010) Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish. Arteriosclerosis, Thrombosis and Vascular Biology, 30, 1695-702. ISSN 1079-5642.

Gregorieff, A. and Clevers, H. (2010) In situ hybridization to identify gut stem cells. Current Protocols in Stem Cell Biology, Chapter 2, Unit-2F 1. ISSN 1941-7322.

Groen, E. J. and Es van, M. A. and Vught van, P. W. and Spliet, W.G.M. and Engelen-Lee van, J. and Visser de, M. and Wokke, J. H. and Schelhaas, H. J. and Ophoff, R. A. and Fumoto, K. and Pasterkamp, R.J. and Dooijes, D. and Cuppen, E. and Veldink, J. H. and Berg van den, L. (2010) FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands. Archives of Neurology, 67, 224-30. ISSN 0003-9942.

Hermans, K. and Claes, F. and Vandevelde, W. and Zheng, W. and Geudens, I. and Orsenigo, F. and Smet De, F. and Gjini, E. and Anthonis, K. and Ren, B. and Kerjaschki, D. and Autiero, M. and Ny, A. and Simons, M. and Dewerchin, M. and Schulte-Merker, S. and Dejana, E. and Alitalo, K. and Carmeliet, P. (2010) Role of synectin in lymphatic development in zebrafish and frogs. Blood, 116, 3356-66. ISSN 0006-4971.

Homberg, J.R. and Nijman, I.J. and Kuijpers, S. and Cuppen, E. (2010) Identification of genetic modifiers of behavioral phenotypes in serotonin transporter knockout rats. BMC Genet, 11, 37-. ISSN 1471-2156.

Isik, M. and Korswagen, H.C. and Berezikov, E. (2010) Expression patterns of intronic microRNAs in Caenorhabditis elegans. Silence, 1, 5-. ISSN 1758-907X.

Jakobsson, L. and Franco, C. A. and Bentley, K. and Collins, R. T. and Ponsioen, B. and Aspalter, I. M. and Rosewell, I. and Busse, M. and Thurston, G. and Medvinsky, A. and Schulte-Merker, S. and Gerhardt, H. (2010) Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nature Cell Biology, 12, 943-53. ISSN 1465-7392.

Jalink, K. and Rheenen van, J. (2010) Nano-imaging of membrane topography affects interpretations in cell biology. Nature Methods, 7, 486-. ISSN 1548-7091.

Johannes, F. and Wardenaar, R. and Colome-Tatche, M. and Mousson, F. and Graaf de, P. and Mokry, M. and Guryev, V. and Timmers, H. T. and Cuppen, E. and Jansen, R. (2010) Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq. Bioinformatics, 26, 1000-6. ISSN 1367-4803.

Kaaij, L. J. and Ketting, R.F. (2010) Dcr1 tracked down. Developmental Cell, 18, 6-7. ISSN 1534-5807.

Kosinski, C. and Stange, D.E. and Xu, C. and Chan, A. S. and Ho, C. and Yuen, S. T. and Mifflin, R. C. and Powell, D. W. and Clevers, H. and Leung, S. Y. and Chen, X.N. (2010) Indian hedgehog regulates intestinal stem cell fate through epithelial-mesenchymal interactions during development. Gastroenterology, 139, 893-903. ISSN 0016-5085.

Li, L. and Clevers, H. (2010) Coexistence of quiescent and active adult stem cells in mammals. Science, 327, 542-5. ISSN 0036-8075.

Linsen, S.E.V. and Wit de, E. and Bruijn de, E. and Cuppen, E. (2010) Small RNA expression and strain specificity in the rat. BMC Genomics, 11, 249-. ISSN 1471-2164.

Lyddon, R. and Cuppen, E. and Haroutunian, V. and Siever, L. J. and Dracheva, S. (2010) No link of serotonin 2C receptor editing to serotonin transporter genotype. Neuroreport, 21, 1080-4. ISSN 0959-4965.

Mahmoudi, T. and Boj, S.F. and Hatzis, P. and Li, V.S. and Taouatas, N. and Vries, R.G.J. and Teunissen, H. and Begthel, H.L. and Korving, J. and Mohammed, S. and Heck, A. and Clevers, H. (2010) The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasis. PLoS Biology, 8, e1000539-. ISSN 1544-9173.

Mallo, M. and Wellik, D. M. and Deschamps, J. (2010) Hox genes and regional patterning of the vertebrate body plan. Developmental Biology, 344, 7-15. ISSN 0012-1606.

Martins da Costa, P. A. and Salic, K. and Gladka, M.M. and Armand, A.S. and Leptidis, S. and Azzouzi el, H. and Hansen, A. and Roo Coenen-de, C. J. and Bierhuizen, M.F.A. and Nagel van der, R. and Kuik van, J. and Weger de, R. and Bruin de, A. and Condorelli, G. and Arbones, M. L. and Eschenhagen, T. and Windt de, L.J. (2010) MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling. Nature Cell Biology, 12, 1220-7. ISSN 1465-7392.

Menke, V. and Es van, J.H. and Lau de, W.B.M. and Born van den, M.M.W. and Kuipers, E. J. and Siersema, P. D. and Bruin de, R. W. and Kusters, J. G. and Clevers, H. (2010) Conversion of metaplastic Barrett's epithelium into post-mitotic goblet cells by gamma-secretase inhibition. Disease Models & Mechanisms, 3, 104-10. ISSN 1754-8403.

Mokry, M. and Feitsma, H. and Nijman, I.J. and Bruijn de, E. and Zaag van der, P. J. and Guryev, V. and Cuppen, E. (2010) Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries. Nucleic Acids Research, 38, e116-. ISSN 0305-1048.

Mokry, M. and Hatzis, P. and Bruijn de, E. and Koster, J. and Versteeg, R. and Schuijers, J. and Wetering van de, M.L. and Guryev, V. and Clevers, H. and Cuppen, E. (2010) Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles. PLoS One, 5, e15092-. ISSN 1932-6203.

Mulder De, K. and Berezikov, E. (2010) Tracing the evolution of tissue identity with microRNAs. Genome Biology, 11, 111-. ISSN 1474-760X.

Ng, S.S. and Mahmoudi, T. and Li, V.S. and Hatzis, P. and Boersema, P. J. and Mohammed, S. and Heck, A. and Clevers, H. (2010) MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway. Biological Chemistry, 391, 171-80. ISSN 1431-6730.

Nijman, I.J. and Mokry, M. and Boxtel van, R. and Toonen, P.W. and Bruijn de, E. and Cuppen, E. (2010) Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples. Nature Methods, 7, 913-5. ISSN 1548-7091.

Oerlemans, M. I. and Goumans, M.J. and Middelaar van, B. and Clevers, H. and Doevendans, P.A. and Sluijter, J. P. (2010) Active Wnt signaling in response to cardiac injury. Basic Research in Cardiology, 105, 631-41. ISSN 0300-8428.

Pedrioli, D. M. and Karpanen, T. and Dabouras, V. and Jurisic, G. and Hoek van de, G. and Shin, J. W. and Marino, D. and Kalin, R. E. and Leidel, S. and Cinelli, P. and Schulte-Merker, S. and Brandli, A. W. and Detmar, M. (2010) miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo. Molecular and Cellular Biology, 30, 3620-34. ISSN 0270-7306.

Pooresmaeili, A. and Herrero, J.L and Self, M.W. and Roelfsema, P.R. and Thiele, A. (2010) Suppressive lateral interactions at parafoveal representations in primary visual cortex. Journal of Neuroscience, 30, 12745-12758. ISSN 0270-6474.

Pooresmaeili, A. and Poort, J. and Thiele, A. and Roelfsema, P.R. (2010) Separable codes for attention and luminance contrast in the primary visual cortex. Journal of Neuroscience, 30, 12701-12711. ISSN 0270-6474.

Qiu, W. and Wang, X. and Leibowitz, B. and Liu, H. and Barker, N. and Okada, H. and Oue, N. and Yasui, W. and Clevers, H. and Schoen, R. E. and Yu, J. and Zhang, L. (2010) Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 107, 20027-32. ISSN 0027-8424.

Quyn, A. J. and Appleton, P. L. and Carey, F. A. and Steele, R. J. and Barker, N. and Clevers, H. and Ridgway, R.A. and Sansom, O.J. and Nathke, I. S. (2010) Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue. Cell Stem Cell, 6, 175-81. ISSN 1934-5909.

Rieden In der, P.M. and Vilaspasa, F.L. and Durston, A.J. (2010) Xwnt8 directly initiates expression of labial Hox genes. Developmental Dynamics, 239, 126-39. ISSN 1058-8388.

Rooijen van, E. and Voest, E.E. and Logister, I. and Bussmann, J. and Korving, J. and Eeden van, F. J. and Giles, R.H. and Schulte-Merker, S. (2010) von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish. Disease Models & Mechanisms, 3, 343-53. ISSN 1754-8403.

Roukens, M. G. and Alloul-Ramdhani, M. and Baan, B. and Kobayashi, K. and Peterson-Maduro, J. and Dam van, H.J. and Schulte-Merker, S. and Baker, D. A. (2010) Control of endothelial sprouting by a Tel-CtBP complex. Nature Cell Biology, 12, 933-42. ISSN 1465-7392.

Sato, T. and Es van, J.H. and Snippert, H.J.G. and Stange, D.E. and Vries, R.G.J. and Born van den, M.M.W. and Barker, N. and Shroyer, N. F. and Wetering van de, M.L. and Clevers, H. (2010) Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature. ISSN 0028-0836.

Silhankova, M. and Port, F. and Harterink, M. and Basler, K. and Korswagen, H.C. (2010) Wnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells. EMBO Journal, 29, 4094-105. ISSN 0261-4189.

Silva Sartori da, M. A. and Tee, J.M. and Paridaen, J.T.M. and Brouwers, A.M. and Runtuwene, V.J. and Zivkovic, D. and Diks, S.H. and Guardavaccaro, D. and Peppelenbosch, M.P. (2010) Essential role for the d-Asb11 cul5 Box domain for proper notch signaling and neural cell fate decisions in vivo. PLoS One, 5, e14023-. ISSN 1932-6203.

Silva Sartori da, M. A. and Tee, J.M. and Paridaen, J.T.M. and Brouwers, A.M. and Runtuwene, V.J. and Zivkovic, D. and Diks, S.H. and Wolfswinkel van, J.C. and Ketting, R.F. (2010) Essential role for the d-Asb11 cul5 Box domain for proper notch signaling and neural cell fate decisions in vivo le of small non-coding RNAs in genome stability and chromatin organization. Journal of Cell Science, 5, e14023-. ISSN 0021-9533.

Sleigh, J. N. and Buckingham, S. D. and Esmaeili, B. and Viswanathan, M. and Cuppen, E. and Westlund, B. M. and Sattelle, D. B. (2010) A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds. Human Molecular Genetics, 20, 245-60. ISSN 0964-6906.

Snippert, H.J.G. and Haegebarth, A. and Kasper, M. and Jaks, V. and Es van, J.H. and Barker, N. and Wetering van de, M.L. and Born van den, M.M.W. and Begthel, H.L. and Vries, R.G.J. and Stange, D.E. and Toftgard, R. and Clevers, H. (2010) Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin. Science, 327, 1385-9. ISSN 0036-8075.

Snoeren, E. and Chan, J.Y. and Bovens, A. and Cuppen, E. and Waldinger, M. and Olivier, B. and Oosting, R. (2010) Serotonin transporter null mutation and sexual behavior in female rats: 5-HT1A receptor desensitization. Journal of Sexual Medicine, 7, 2424-34. ISSN 1743-6095.

Tauriello, D. V. and Haegebarth, A. and Kuper, I. and Edelmann, M. J. and Henraat, M. and Dijk Canninga-van, M. R. and Kessler, B. M. and Clevers, H. and Maurice, M.M. (2010) Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl. Molecular Cell, 37, 607-19. ISSN 1097-2765.

Tournoij, E. and Weber, G. J. and Akkerman, J. W. and Groot de, P. G. and Zon, L. and Moll, F. L. and Schulte-Merker, S. (2010) Mlck1a is expressed in zebrafish thrombocytes and is an essential component of thrombus formation. Journal of Thrombosis and Haemostasis, 8, 588-95. ISSN 1538-7933.

Verheyen, E. M. and Clevers, H. (2010) Wnts as self-renewal factors: mammary stem cells and beyond. Cell Stem Cell, 6, 494-5. ISSN 1934-5909.

Verzi, M. P. and Hatzis, P. and Sulahian, R. and Philips, J. and Schuijers, J. and Shin, H.D. and Freed, E. and Lynch, J. P. and Dang, D. T. and Brown, M. and Clevers, H. and Liu, X. S. and Shivdasani, R. A. (2010) TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proceedings of the National Academy of Sciences of the United States of America, 107, 15157-62. ISSN 0027-8424.

Vries, R.G.J. and Huch, M. and Clevers, H. (2010) Stem cells and cancer of the stomach and intestine. Molecular Oncology, 4, 373-84. ISSN 1574-7891.

Wansleeben, C. and Feitsma, H. and Montcouquiol, M. and Kroon, C. and Cuppen, E. and Meijlink, F.C.P.W. (2010) Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b. Development, 137, 1067-73. ISSN 0950-1991.

Wansleeben, C. and Feitsma, H. and Tertoolen, L.G.J. and Kroon, C. and Guryev, V. and Cuppen, E. and Meijlink, F.C.P.W. (2010) A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction. International journal of developmental biology, 54, 1465-71. ISSN 0214-6282.

Wijchers, P. J. and Laat de, W. (2010) Genome organization influences partner selection for chromosomal rearrangements. Trends in Genetics. ISSN 0168-9525.

Wijk van, J. P. and Hoepelman, A. I. and Koning de, E. and Dallinga-Thie, G. and Rabelink, T. J. and Cabezas, M. C. (2010) Differential effects of rosiglitazone and metformin on postprandial lipemia in patients with HIV-lipodystrophy. Arteriosclerosis, Thrombosis and Vascular Biology, 31, 228-33. ISSN 1079-5642.

Witschi, R. and Johansson, T. and Morscher, G. and Scheurer, L. and Deschamps, J. and Zeilhofer, H. U. (2010) Hoxb8-Cre mice: A tool for brain-sparing conditional gene deletion. Genesis, 48, 596-602. ISSN 1526-954X.

Wolfswinkel van, J.C. and Ketting, R.F. (2010) The role of small non-coding RNAs in genome stability and chromatin organization. Journal of Cell Science, 123, 1825-39. ISSN 0021-9533.

Chapter/Part of Book

Clevers, H. (2010) Stamceltherapie maakt eerste beloften waar. In: Gezondgids.

Doctoral Thesis

Boxtel van, R. (2010) Rat reverse genetics: generation and characterization of chemically induced rat mutants.

Faro, A. (2010) Heads and Tails of endoderm development & adult tissue homeostasis in zebrafish.

Gjini, E. (2010) Regulation of Angiogenesis and lymphangiogenesis in Zebrafish.

Herpers, R. (2010) Genetic regulation of vascular development - building the Zebrafish Vascular Tree.

Linsen, S.E.V. (2010) Small RNA evolution and distribution patterns based on digital gene expression profiling.

Mul, J.D. (2010) Rat models in obesity research: functions for PMCH and LPIN1 in energy homeostasis regulation.

Ng, S.S. (2010) Unravelling the molecular mechanisms of the canonical Wnt signalling pathway.

Pater de, E.M. (2010) Growth of the Zebrafish Heart.

Tee, J.M. (2010) Cell Fate Determination in Zebrafish Embryonic and Adult Muscle Development.

Tournoij, E. (2010) Platelet Activation in Vascular Disease: from Animal Studies to Clinical Consequences.

Vacaru, A. (2010) RPTPa-mediated activation of Src.

Wansleeben, C. (2010) A mutagenesis screen in the mouse: Identification of novel gene functions in embryonic development.

This list was generated on Tue Jul 29 17:19:45 2014 CEST.