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Items where Institute is "Hubrecht Instituut" and Year is 2011

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Bakkers, J. (2011) Zebrafish as a model to study cardiac development and human cardiac disease. Cardiovascular Research, 91, 279-88. ISSN 0008-6363.

Basak, O. and Clevers, H. (2011) Neural stem cells for diabetes cell-based therapy. EMBO Molecular Medicine, 3, 698-700. ISSN 1757-4676.

Boogerd, C.J. and Wong, L.Y. and Boogaard van den, M. and Bakker, M.A.J. and Tessadori, F. and Bakkers, J. and 't Hoen, J. and Moorman, A. F. and Christoffels, V.M. and Barnett, P. (2011) Sox4 mediates Tbx3 transcriptional regulation of the gap junction protein Cx43. Cellular and Molecular Life Sciences, 68, 3949-61. ISSN 1420-682X.

Bos, F. L. (2011) Genetic regulation of angiogenesis and lymphangiogenesis.

Bos, F. L. and Caunt, M. and Peterson-Maduro, J. and Planas-Paz, L. and Kowalski, J. and Karpanen, T. and Impel van, A. and Tong, R. and Ernst, J. A. and Korving, J. and Es van, J.H. and Lammert, E. and Duckers, H.J. and Schulte-Merker, S. (2011) CCBE1 is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-C in vivo. Circulation Research, 109, 486-91. ISSN 0009-7330.

Buske, P. and Galle, J. and Barker, N. and Aust, G. and Clevers, H. and Loeffler, M. (2011) A comprehensive model of the spatio-temporal stem cell and tissue organisation in the intestinal crypt. PLoS Computational Biology, 7, e1001045-. ISSN 1553-734X.

Bussmann, J. and Schulte-Merker, S. (2011) Rapid BAC selection for tol2-mediated transgenesis in zebrafish. Development, 138, 4327-32. ISSN 0950-1991.


Cheng, C.Y. and Tempel, D. and Dekker Den, W. K. and Haasdijk, R. and Chrifi, I. and Bos, F. L. and Wagtmans, K. and Kamp van de, E. H. and Blonden, L. and Biessen, E. A. and Moll, F. L. and Pasterkamp, G. and Serruys, P. W. and Schulte-Merker, S. and Duckers, H.J. (2011) Ets2 determines the inflammatory state of endothelial cells in advanced atherosclerotic lesions. Circulation Research, 109, 382-95. ISSN 0009-7330.


Eacker, S. M. and Keuss, M. J. and Berezikov, E. and Dawson, V. L. and Dawson, T. (2011) Neuronal activity regulates hippocampal miRNA expression. PLoS One, 6, e25068-. ISSN 1932-6203.

Edwards, C.J. and Ginja, C. and Kantanen, J. and Perez-Pardal, L. and Tresset, A. and Stock, F. and Gama, L.T. and Penedo, M.C. and Bradley, D.G. and Lenstra, J.A. and Nijman, I.J. (2011) Dual origins of dairy cattle farming--evidence from a comprehensive survey of European Y-chromosomal variation. PLoS One, 6, e15922-. ISSN 1932-6203.

Eekelen van, M.J.L. (2011) Protein-tyrosine phosphatases in zebrafish gastrulation.


Farhan, H. and Rabouille, C. (2011) Signalling to and from the secretory pathway. Journal of Cell Science, 124, 171-80. ISSN 0021-9533.

Fiedler, J. and Jazbutyte, V. and Kirchmaier, B. C. and Gupta, S. K. and Lorenzen, J. and Hartmann, D. and Galuppo, P. and Kneitz, S. and Pena, J. and Sohn-Lee, C. and Loyer, X. and Soutschek, J. and Brand, T. and Tuschl, T. and Heineke, J. and Martin, U. and Schulte-Merker, S. and Ertl, G. and Engelhardt, S. and Bauersachs, J. and Thum, T. (2011) MicroRNA-24 regulates vascularity after myocardial infarction. Circulation, 124, 720-30. ISSN 0009-7322.


Ghani, S. and Riemke, P. and Schonheit, J. and Lenze, D. and Stumm, J. and Hoogenkamp, M. and Lagendijk, A.K. and Heinz, S.K. and Bonifer, C. and Bakkers, J. and Abdelilah-Seyfried, S. and Hummel, M. and Rosenbauer, F. (2011) Macrophage development from HSCs requires PU.1-coordinated microRNA expression. Blood, 118, 2275-84. ISSN 0006-4971.

Giuliani, F. and Grieve, A. and Rabouille, C. (2011) Unconventional secretion: a stress on GRASP. Current Opinion in Cell Biology, 23, 498-504. ISSN 0955-0674.

Gjini, E. and Hekking, L. H. and Kuchler, A. and Saharinen, P. and Wienholds, E. and Post, J. and Alitalo, K. and Schulte-Merker, S. (2011) Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity. Disease Models & Mechanisms, 4, 57-66. ISSN 1754-8403. Supplementary material for this article is available at http:/​/​​lookup/​suppl/​doi:10.1242/​dmm.005033/​-/​DC1.

Gutierrez, A. and Grebliunaite, R. and Feng, H. and Kozakewich, E. and Zhu, S. and Guo, F. and Payne, E. and Mansour, M. and Dahlberg, S. E. and Neuberg, D. S. and Hertog den, J. and Prochownik, E. V. and Testa, J. R. and Harris, M. and Kanki, J. P. and Look, A. T. (2011) Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia. Journal of Experimental Medicine, 208, 1595-603. ISSN 0022-1007.


Harakalova, M. and Nijman, I.J. and Medic, J. and Mokry, M. and Renkens, I. and Blankensteijn, J. D. and Kloosterman, W.P. and Baas, A. F. and Cuppen, E. (2011) Genomic DNA pooling strategy for next-generation sequencing-based rare variant discovery in abdominal aortic aneurysm regions of interest-challenges and limitations. Journal of Cardiovascular Translational Research, 4, 271-80. ISSN 1937-5395.

Harterink, M. and Kim, D. H. and Middelkoop, T. C. and Doan, T. D. and Oudenaarden van, A. and Korswagen, H.C. (2011) Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein. Development, 138, 2915-24. ISSN 0950-1991.

Held, N. and Smits, B.M. and Gockeln, R. and Schubert, S. and Nave, H. and Northrup, E. and Cuppen, E. and Hedrich, H.J. and Wedekind, D. (2011) A mutation in Myo15 leads to Usher-like symptoms in LEW/Ztm-ci2 rats. PLoS One, 6, e15669-. ISSN 1932-6203.

Houdt, W.J. and Emmink, B.L. and Pham, T. and Piersma, S. and Verheem, A. and Vries, R.G.J. and Fratantoni, S. and Pronk, A. and Clevers, H. and Rinkes, I.H. and Jimenez, C.R. and Kranenburg, O. (2011) Comparative Proteomics of Colon Cancer Stem Cells and Differentiated Tumor Cells Identifies BIRC6 as a Potential Therapeutic Target. Molecular and Cellular Proteomics, 10, M111-011353. ISSN 1535-9476. © the American Society for Biochemistry and Molecular Biology..


Kasher, P.R. and Namavar, Y. and Tijn van, P. and Fluiter, K. and Sizarov, A. and Kamermans, M. and Grierson, A.J. and Zivkovic, D. and Baas, F. (2011) Impairment of the tRNA-splicing endonuclease subunit 54 (tsen54) gene causes neurological abnormalities and larval death in zebrafish models of pontocerebellar hypoplasia. Human Molecular Genetics, 20, 1574-84. ISSN 0964-6906.

Ketting, R.F. (2011) MicroRNA Biogenesis and Function: An overview. In: Regulation of microRNAs Ed: H Grosshans Landes Bioscience and Springer.

Kloosterman, W.P. and Guryev, V. and Roosmalen van, M. and Duran, K.J. and Bruijn de, E. and Bakker, S. and Letteboer, T. and Nesselrooij van, B. and Hochstenbach, R. and Poot, M. and Cuppen, E. (2011) Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline. Human Molecular Genetics, 20, 1916-24. ISSN 0964-6906.

Kloosterman, W.P. and Hoogstraat, M. and Paling, O. and Tavakoli-Yaraki, M. and Renkens, I. and Vermaat, J.E. and Roosmalen van, M. and Lieshout van, S. and Nijman, I.J. and Roessingh, W. and Slot Van't, R. and Belt van de, J. and Guryev, V. and Koudijs, M.J. and Voest, E.E. and Cuppen, E. (2011) Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer. Genome Biology, 12, R103-. ISSN 1474-760X.

Kondylis, V. and Tang, Y. and Fuchs, F. and Boutros, M. and Rabouille, C. (2011) Identification of ER proteins involved in the functional organisation of the early secretory pathway in Drosophila cells by a targeted RNAi screen. PLoS One, 6, e17173-. ISSN 1932-6203.

Krueger, J. and Liu, D. and Scholz, K. and Zimmer, A. and Shi, Y. and Klein, C. and Siekmann, A. and Schulte-Merker, S. and Cudmore, M. and Ahmed, A. and Noble le, F. (2011) Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo. Development, 138, 2111-20. ISSN 0950-1991.


Lagendijk, A.K. and Goumans, M.J. and Burkhard, S. B. and Bakkers, J. (2011) MicroRNA-23 restricts cardiac valve formation by inhibiting Has2 and extracellular hyaluronic acid production. Circulation Research, 109, 649-57. ISSN 0009-7330.


Matsumaru, D. and Haraguchi, R. and Miyagawa, S. and Motoyama, J. and Nakagata, N. and Meijlink, F.C.P.W. and Yamada, G. (2011) Genetic analysis of Hedgehog signaling in ventral body wall development and the onset of omphalocele formation. PLoS One, 6, e16260-. ISSN 1932-6203.

Mokry, M. and Nijman, I.J. and Dijken van, A. and Benjamins, R. and Heidstra, R. and Scheres, B. and Cuppen, E. (2011) Identification of factors required for meristem function in Arabidopsis using a novel next generation sequencing fast forward genetics approach. BMC Genomics, 12, 256-. ISSN 1471-2164.

Mul, J.D. and Fleur la, S. E. and Toonen, P.W. and Afrasiab-Middelman, A. and Binnekade, R. and Schetters, D. and Verheij, M. M. and Sears, R. and Homberg, J.R. and Schoffelmeer, A.N.M. and Adan, R.A. and DiLeone, R. J. and Vries, T. and Cuppen, E. (2011) Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat. PLoS One, 6, e19600-. ISSN 1932-6203.


Palma Di, S. and Stange, D.E. and Wetering van de, M.L. and Clevers, H. and Heck, A. and Mohammed, S. (2011) Highly sensitive proteome analysis of FACS-sorted adult colon stem cells. Journal of Proteome Research, 10, 3814-9. ISSN 1535-3893.

Pannekoek, W. J. and Dijk van, J. and Chan, O. Y. and Huveneers, S. and Linnemann, J. R. and Spanjaard, E. and Brouwer E. M., P. and Meer van der, A. J. and Zwartkruis, F.J. and Rehmann, H. and Rooij de, J. and Bos, J. (2011) Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control. Cellular Signalling, 23, 2056-64. ISSN 0898-6568.

Pereboom, T. C. and Weele van, L. J. and Bondt, A. and MacInnes, A.W. (2011) A zebrafish model of dyskeratosis congenita reveals hematopoietic stem cell formation failure resulting from ribosomal protein-mediated p53 stabilization. Blood, 118, 5458-65. ISSN 0006-4971.

Poell, J. B. and Haastert van, R. J. and Cerisoli, F. and Bolijn, A. S. and Timmer, L. M. and Diosdado-Calvo, B. and Meijer, G. A. and Puijenbroek van, A. A. and Berezikov, E. and Schaapveld, R. Q. and Cuppen, E. (2011) Functional microRNA screening using a comprehensive lentiviral human microRNA expression library. BMC Genomics, 12, 546-. ISSN 1471-2164.


Runtuwene, V.J. and Eekelen van, M.J.L. and Overvoorde, J. and Rehmann, H. and Yntema, H.G. and Nillesen, W.M. and Haeringen van, A. and Burgt van der, I. and Burgering, B. and Hertog den, J. (2011) Noonan syndrome gain-of-function mutations in NRAS cause zebrafish gastrulation defects. Disease Models & Mechanisms, 4, 393-9. ISSN 1754-8403.

Ryazansky, S. S. and Gvozdev, V. A. and Berezikov, E. (2011) Evidence for post-transcriptional regulation of clustered microRNAs in Drosophila. BMC Genomics, 12, 371-. ISSN 1471-2164.


Schulte-Merker, S. and Sabine, A. and Petrova, T. V. (2011) Lymphatic vascular morphogenesis in development, physiology, and disease. Journal of Cell Biology, 193, 607-18. ISSN 0021-9525.

Sleigh, J. N. and Buckingham, S. D. and Esmaeili, B. and Viswanathan, M. and Cuppen, E. and Westlund, B. M. and Sattelle, D. B. (2011) A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds. Human Molecular Genetics, 20, 245-60. ISSN 0964-6906.

Smith, K. and Lagendijk, A.K. and Courtney, A. D. and Chen, H. and Paterson, S. and Hogan, B.M. and Wicking, C. and Bakkers, J. (2011) Transmembrane protein 2 (Tmem2) is required to regionally restrict atrioventricular canal boundary and endocardial cushion development. Development, 138, 4193-8. ISSN 0950-1991.

Smith, K. and Noel, E and Thurlings, I. and Rehmann, H. and Chocron, S. and Bakkers, J. (2011) Bmp and nodal independently regulate lefty1 expression to maintain unilateral nodal activity during left-right axis specification in zebrafish. PLoS Genetics, 7, e1002289-. ISSN 1553-7390.

Sylva, M. and Li, V.S. and Buffing, A. A. and Es van, J.H. and Born van den, M.M.W. and Velden van der, S. and Gunst, Q. and Koolstra, J. H. and Moorman, A. F. and Clevers, H. and Hoff van den, M. J. (2011) The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis. PLoS One, 6, e22616-. ISSN 1932-6203.


Tao, S. and Witte de, M. and Bryson-Richardson, R.J. and Currie, P.D. and Hogan, B.M. and Schulte-Merker, S. (2011) Zebrafish prox1b Mutants Develop a Lymphatic Vasculature, and prox1b Does Not Specifically Mark Lymphatic Endothelial Cells. PLoS One, 6, e28934-. ISSN 1932-6203.

Tolhuis, B. and Blom, M. and Kerkhoven, R.M. and Pagie, L. and Teunissen, H. and Nieuwland, M. and Simonis, M. and Laat de, W. and Lohuizen van, M. and Steensel van, B. (2011) Interactions among Polycomb Domains Are Guided by Chromosome Architecture. PLoS Genetics, 7, e1001343-. ISSN 1553-7390.


Velden, Y.U. and Wang, L. and Zevenhoven, J. and Rooijen van, E. and Lohuizen van, M. and Giles, R.H. and Clevers, H. and Haramis, A.P. (2011) The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish. Proceedings of the National Academy of Sciences of the United States of America, 108, 4358-63. ISSN 0027-8424.

Vinke, F. P. and Grieve, A. and Rabouille, C. (2011) The multiple facets of the Golgi reassembly stacking proteins. Biochemical Journal, 433, 423-33. ISSN 0264-6021.


Wansleeben, C. and Gurp van, L.C.A. and Feitsma, H. and Kroon, C. and Rieter, E. and Verberne, M. and Guryev, V. and Cuppen, E. and Meijlink, F.C.P.W. (2011) An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions. PLoS One, 6, e19357-. ISSN 1932-6203.

Wesseling, S. and Essers, P.B. and Koeners, M.P. and Pereboom, T.C. and Braam, B. and Faassen van, E.E. and MacInnes, A.W. and Joles, J.A. (2011) Perinatal exogenous nitric oxide in fawn-hooded hypertensive rats reduces renal ribosomal biogenesis in early life. Frontiers in Genetics, 2. ISSN 1664-8021.


Xiao, Y. and Bedet, C. and Robert, V. J. and Simonet, T. and Dunkelbarger, S. and Rakotomalala, C. and Soete, G. and Korswagen, H.C. and Strome, S. and Palladino, F. (2011) Caenorhabditis elegans chromatin-associated proteins SET-2 and ASH-2 are differentially required for histone H3 Lys 4 methylation in embryos and adult germ cells. Proceedings of the National Academy of Sciences of the United States of America, 108, 8305-10. ISSN 0027-8424.


Zomer, A.W.M. and Beerling, E. and Vlug, E. J. and Rheenen van, J. (2011) Real-time intravital imaging of cancer models. Clinical and Translational Oncology, 13, 848-54. ISSN 1699-048X.

This list was generated on Wed Sep 2 20:58:31 2015 CEST.